Product & ReviewsAntibodies

ASPM / MCPH5 rabbit antibody (pAb)

Product Details

Cat. No.
61205
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Active Motif

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Description

ASPM (abnormal spindle-like microcephaly associated, microcephaly primary type 5, MCPH5) is a protein that participates in spindle organization, spindle positioning and cytokinesis in all dividing cells. ASPM / MCPH5 localizes to centrosomes, spindle poles, and the spindle midbody. It regulates the orientation of the mitotic spindle, which controls whether cells divide symmetrically or asymmetrically. ASPM / MCPH5 is highly expressed in many tumor cell lines and mutations in the gene encoding ASPM / MCPH5 lead to primary microcephaly in humans.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Isotype: IgG

Handling

  • Quantity: 100 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Immunofluorescence (IF)
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