Product & ReviewsAntibodies
ASPM / MCPH5 rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 61206
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
ASPM (abnormal spindle-like microcephaly associated, microcephaly primary type 5, MCPH5) is a protein that participates in spindle organization, spindle positioning and cytokinesis in all dividing cells. ASPM / MCPH5 localizes to centrosomes, spindle poles, and the spindle midbody. It regulates the orientation of the mitotic spindle, which controls whether cells divide symmetrically or asymmetrically. ASPM / MCPH5 is highly expressed in many tumor cell lines and mutations in the gene encoding ASPM / MCPH5 lead to primary microcephaly in humans.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: IgG
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)