Product & ReviewsAntibodies
ATF-1 Antibody
Product Details
- Cat. No.
- 251171
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Activating transcription factor 1 (ATF-1) is a protein that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF-1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF-1 mediates PKA-induced stimulation of CRE-reporter genes. Defects in ATF-1 are linked to angiomatoid fibrous histiocytoma (AFH). AFH is a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Dog (Canine), Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ATF-1.
- Isotype: Rabbit Ig
- Gene: P18846
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)