Product & ReviewsAntibodies
ATF-6 alpha Antibody
Product Details
- Cat. No.
- 252098
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
ATF-6 alpha is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. ATF-6 alpha binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). The binding to ERSE also requires binding of NF-Y to the ERSE. ATF-6 alpha is also be involved in activation of transcription by the serum response factor.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human ATF-6 alpha.
- Isotype: Rabbit Ig
- Gene: P18850
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)