Product & ReviewsAntibodies
ATF2 (Ser490/498) Antibody
Product Details
- Cat. No.
- 252524
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Activating transcription factor 2 (ATF2) is a transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) consensus sequence: 5'-GTGACGT[AC][AG]-3', a sequence present in many viral and cellular promoters. ATF2 binds DNA as a dimer and can form a homodimer in the absence of DNA. ATF2 can form a heterodimer with JUN, and interacts with SMAD3 and SMAD4. Stress induced ATF-dependent transcription is dependent on phosphorylation of ATF.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Rat
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser490/498 of rat ATF2.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: P15336
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)