Product & ReviewsAntibodies
ATM Antibody
Product Details
- Cat. No.
- 200158
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Pig (Swine)
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM.
- Isotype: Rabbit Ig
- Gene: Q13315, NP_000042
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)