ATP6V0C Rabbit pAb
Product Details
- Cat. No.
- A16350
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Immunofluorescence - ATP6V0C Polyclonal Antibody (A16350)
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Description
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
