Atxn7l3 mouse antibody (mAb) (Clone 2ATX-2B1)
Product Details
- Cat. No.
- 61339
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Atxn7l3 (ataxin 7-like 3) is a component of the transcription regulatory histone acetylation (HAT) complex SAGA (Spt-Ada-Gcn5-Acetyltransferase), a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Clone: 2ATX-2B1
- Isotype: IgG1k
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunoprecipitation (IP)
- Western Blotting (WB)