Aurora A Antibody
Product Details
- Cat. No.
- 251910
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Aurora A (Serine/threonine-protein kinase 6) contributes to the regulation of cell cycle progression and is required for normal mitosis. Aurora A associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. It phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Aurora A plays a role in microtubule remodeling during neurite extension, and is important for microtubule formation and/or stabilization.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide from human Aurora A.
- Isotype: Rabbit Ig
- Gene: O14965
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)