Product & ReviewsAntibodies
Aurora B rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 39262
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Aurora B is a Ser/Thr kinase that is part of the chromosomal passenger complex that associates with chromosomes and is an important regulator of mitosis and meiosis. Aurora B becomes concentrated at the centromere during the onset of mitosis, but relocates to the spindle midzone during anaphase. Aurora B phosphorylates a number of substrates, including INCENP, CENP-A, and histone H3. Misregulation of Aurora B activity can lead to chromosome instability and is implicated in a number of cancers.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Not Species Specific, Human, Mouse
- Isotype: Serum
Handling
- Quantity: 10 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)