Product & ReviewsAntibodies
BACE Antibody
Product Details
- Cat. No.
- 250553
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Beta-amyloid precursor protein cleaving enzyme (BACE) is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE cleaves at the N-terminus of the amyloid-beta peptide sequence, between residues 671 and 672 of APP, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BACE.
- Isotype: Rabbit Ig
- Gene: P56817
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)