BAIAP2 Rabbit pAb
Product Details
- Cat. No.
- A5337
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - BAIAP2 antibody (A5337)
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Description
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Rat
