Product & ReviewsAntibodies

Bak Rabbit mAb

Product Details

Cat. No.
A10754
Type
Primary Antibody
Clonality
Monoclonal
Host
Rabbit
ABclonal Technology

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Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Biological Information

  • Clonality: Monoclonal
  • Host: Rabbit
  • Reactivity: Human

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