Product & ReviewsAntibodies

BAZ2A antibody

Product Details

Cat. No.
orb382907
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Biorbyt

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Description

Rabbit polyclonal antibody to BAZ2A also known as TTFI5 or Tip5 whose expression can be detected in the heart and kidney but it is highly expressive in the placenta and pancreas. It is found in the nuclear speck. It is found in the microtubule cytoskeleton. BAZ2A plays an extensive role in RNA polymerase I CORE element sequence-specific DNA binding and chromatin remodeling. It binds with a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases; leading to heterochromatin formation and transcriptional silencing.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Pig (Swine), Rat
  • Clone: NULL
  • Conjugate: Unconjugated
  • Isotype: IgG
  • Gene: 11176

Handling

  • Quantity: 100 ?g; 200 ?g
  • Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
  • Buffer: 10 mM PBS; 0.02% sodium azide

Applications

  • Immunofluorescence (IF)
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Western Blotting (WB)
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