Product & ReviewsAntibodies

BCL11A Rabbit pAb

Product Details

Cat. No.
A5445
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
ABclonal Technology

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse

Handling

    Applications

      Specificity rating
      Sensitivity rating
      Quality rating
      Write your own review

      Product Overview

      Links