Product & ReviewsAntibodies
BCRP Antibody
Product Details
- Cat. No.
- 250556
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Breast cancer resistance protein (BCRP) is a xenobiotic transporter with an important role in the exclusion of xenobiotics from the brain. BCRP is also involved in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Dog (Canine), Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BCRP.
- Isotype: Rabbit Ig
- Gene: Q9UNQ0
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)