Product & ReviewsAntibodies

Beta-Amyloid [1-40] Antibody

Product Details

Cat. No.
250923
Type
Primary Antibody
Clonality
Polyclonal
Host
Mouse
Abbiotec

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Description

Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This fragment is the amino terminus (1-40) of beta-amyloid.

Biological Information

  • Clonality: Polyclonal
  • Host: Mouse
  • Reactivity: Human, Mouse, Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing the sequence (1-40) of human Beta Amyloid.
  • Isotype: Mouse Ig
  • Gene: P05067

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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