Product & ReviewsAntibodies
Beta-ARK-1 Antibody
Product Details
- Cat. No.
- 251577
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Beta-ARK-1 is a key regulator of LPAR1 signaling. Beta-ARK-1 competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Beta-ARK-1 desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Beta-ARK-1 is expressed in peripheral blood leukocytes.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Beta-ARK-1 A.
- Isotype: Rabbit Ig
- Gene: P25098
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)