Product & ReviewsAntibodies
Bim (1C2C8) Antibody
Product Details
- Cat. No.
- 253268
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Antigen: Amino acids 2 to 198 of human Bim.
- Clone: 1C2C8
- Isotype: mouse IgG1
- Gene: NP_619527
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Western Blotting (WB)