Product & ReviewsAntibodies

Bim (1C2H4) Antibody

Product Details

Cat. No.
253269
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse, Rat
  • Antigen: Amino acids 2 to 198 of human Bim.
  • Clone: 1C2H4
  • Isotype: mouse IgG1
  • Gene: NP_619527

Handling

  • Quantity: 0.1 mg
  • Storage: Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunocytochemistry (ICC)
  • Western Blotting (WB)
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