Product & ReviewsAntibodies
BIN1 Antibody
Product Details
- Cat. No.
- 251712
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Box-dependent myc-interacting protein 1 (BIN1) is involved in regulation of synaptic vesicle endocytosis. BIN1 acts as a tumor suppressor and inhibits malignant cell transformation. Defects in BIN1 are the cause of centronuclear myopathy autosomal recessive (ARCNM), also known as autosomal recessive myotubular myopathy. Centronuclear myopathies are congenital muscle disorders characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: Recombinant polypeptide encompassing the center region of human BIN1.
- Clone: BN-1
- Isotype: Mouse IgG2b
- Gene: O00499
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)