Product & ReviewsAntibodies
BK Channel Antibody
Product Details
- Cat. No.
- 250561
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The BK channel (calcium-activated potassium channel subunit alpha-1 or KCNMA1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). BK channel is also activated by the concentration of cytosolic Mg(2+). BK channel has a key role in controlling excitability in a numerous systems, such as smooth muscle contraction, tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. Defects in KCNMA1 are the cause of generalized epilepsy and paroxysmal dyskinesia (GEPD).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Human, Monkey, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BK channel.
- Isotype: Rabbit Ig
- Gene: Q12791
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)