Product & ReviewsAntibodies

BK channel (C-term) Antibody

Product Details

Cat. No.
251351
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

The BK channel (calcium-activated potassium channel subunit alpha-1 or KCNMA1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). BK channel is also activated by the concentration of cytosolic Mg(2+). BK channel has a key role in controlling excitability in a numerous systems, such as smooth muscle contraction, tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. Defects in KCNMA1 are the cause of generalized epilepsy and paroxysmal dyskinesia (GEPD).

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Chicken, Dog (Canine), Drosophila melanogaster, Human, Mouse, Rabbit (Lapine), Rat, Sheep (Ovine), Zebrafish
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BK Channel.
  • Isotype: Rabbit Ig
  • Gene: Q12791

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
Specificity rating
Sensitivity rating
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