Product & ReviewsAntibodies

BLK (9D10) Antibody

Product Details

Cat. No.
252670
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

BLK (B lymphoid tyrosine kinase) is a 505-amino acid protein (~56KDa), belongs to the Src non-receptor tyrosine kinases family. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: Purified recombinant fragment of BLK expressed in E. coli.
  • Clone: 9D10B7H6,9D10A8F8
  • Isotype: Mouse IgG1
  • Gene: P51451

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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