BRD4 rabbit antibody (pAb), sample
Product Details
- Cat. No.
- 39910
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
BRD4 (Bromodomain-containing protein 4, aka HUNK1) is a chromatin-associated protein with two bromo domains that binds acetylated histone H3 and H4. BRD4 is homologous to Xenopus MCAP, and like MCAP, BRD4 associates with chromosomes during mitosis, predominantly in the non-centromeric regions. A chromosomal aberration involving BRD4 (producing a BRD4-NUT fusion protein) is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. BRD4 is involved in the expression of extracellular matrix gene expression, and its misregulation may be involved in breast cancer progression.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Isotype: IgG
Handling
- Quantity: 10 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Specificity: 5
Applications
- Chromatin Immunoprecipitation (ChIP)
- Western Blotting (WB)
The results are reproducible.
Immunoprecipitation
BRD4-Rabbit antibody (pAb) is very sensitive and very specific for the detecting the low abundance of proteins present in the cells. It has worked wonderfully for Immunoprecipitation experiments that I pulled down the crosslinked species.
Review Date: 30 Jan 2017 | Active Motif