Product & ReviewsAntibodies
c-Jun Antibody
Product Details
- Cat. No.
- 250606
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
c-Jun/AP-1 (Transcription factor AP-1) forms the AP-1 early response transcription factor in combination with c-Fos. It is activated by double phosphorylation via the JNK pathway, and by PRKDC, but also has a phosphorylation-independent function. c-Jun binds to the enhancer heptamer motif 5'TGA[CG]TCA-3'. It interacts with numerous proteins that may effect its activity including but not limited to FOS, BATF3, HIVEP3, SMAD3/SMAD4, MYBBP1A, SP1, SPIB, TCF20, COPS5, DSIPI, THIF1, ERG, CREB binding protein, Retinoblastoma protein, BRCA1, TATA binding protein, MAPK8, RUNX proteins, STAT1, BCL.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human c-Jun.
- Isotype: Rabbit Ig
- Gene: P05412
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)