Product & ReviewsAntibodies
c-Myc Antibody
Product Details
- Cat. No.
- 251334
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The Myc proto-oncogene protein (c-Myc) participates in the regulation of gene transcription. C-Myc is a transcription factor that binds DNA containing the core sequence 5'-CACGATG-3' but also in a non-specific manner. c-Myc activates genes related to cell growth. Overexpression of c-Myc is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC is a cause of a B-cell chronic lymphocytic leukemia. This antibody recognizes the C-term c-Myc peptide (EQKLISEEDL) used to express c-Myc-tagged fusion proteins.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the leucine zipper region of human c-Myc.
- Isotype: Rabbit Ig
- Gene: P01106
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)