Product & ReviewsAntibodies
C1 Inhibitor Antibody
Product Details
- Cat. No.
- 250122
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The complement C1 inhibitor controls the activation of the C1 complex by forming a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. This process regulates important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Deficiencies in C1 inhibitor cause hereditary angiodema (HAE/HANE), a disorder characterized by episodic local subcutaneous edema and submucosal edema involving the upper respiratory and gastrointestinal tracts. This antibody recognizes human complement C1 inhibitor by ELISA.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified human complement C1 inhibitor protein
- Clone: KT28
- Isotype: mouse IgG1
- Gene: P05155, NP_000053
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)