Product & ReviewsAntibodies
C3 Complement Antibody
Product Details
- Cat. No.
- 250121
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The complement component C3 plays a central role in the activation of the complement system. C3 activation by the C3 convertase is the central reaction in both classical and alternative complement pathways. Cleaved C3 produces C3a anaphylatoxin, a mediator of local inflammatory process, and C3b, which binds to cell surface carbohydrates and immune aggregates. Genetic variation in C3 is associated with susceptibility to age-related macular degeneration 9 (ARMD9). This antibody recognizes the human complement C3 in ELISA.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified human complement C3 protein
- Clone: KT17
- Isotype: Mouse IgG2b
- Gene: P01024, NP_000055
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)