Product & ReviewsAntibodies
Caldesmon Antibody
Product Details
- Cat. No.
- 251716
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Caldesmon is an actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells. Caldesmon stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Caldesmon Iinteracts with actin, myosin, two molecules of tropomyosin and with calmodulin. Caldesmon also plays an essential role during cellular mitosis and receptor capping.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: Caldesmon from turkey gizzard.
- Isotype: Mouse IgG1
- Gene: Q05682
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)