Calpain-6 Antibody
Product Details
- Cat. No.
- 252118
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Calpains are calcium-dependent intracellular nonlysosomal proteases that are believed to participate in signal transduction. In vertebrates, five different calpains have so far been identified, of which three ( μ-, m-, and μ/m-calpain) are ubiquitously expressed while the other two, nCL-1 (p94) and nCL-2, exhibit a restricted tissue distribution. Calpain-6 possesses most of the residues conserved in calpain family members but the C-terminal region lacks any homology to the calmodulin-like domain of other vertebrate calpains. Calpain-6 lacks critical active site residues and is not proteolytically active. Calpain-6 is highly expressed in the placenta sample.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human calpain-6.
- Isotype: Rabbit Ig
- Gene: Q9Y6Q1
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)