Product & ReviewsAntibodies

Caspase-1 Antibody

Product Details

Cat. No.
251903
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Caspase-1 is a thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Caspase-1 important for defense against pathogens. Caspase-1 cleaves and activates sterol regulatory element binding proteins (SREBPs), and also promotes apoptosis. Caspase-1 is specifically inhibited by the cowpox virus Crma protein

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-1.
  • Isotype: Rabbit Ig
  • Gene: P29466

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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