Product & ReviewsAntibodies
Caspase-1 Antibody
Product Details
- Cat. No.
- 251903
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Caspase-1 is a thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Caspase-1 important for defense against pathogens. Caspase-1 cleaves and activates sterol regulatory element binding proteins (SREBPs), and also promotes apoptosis. Caspase-1 is specifically inhibited by the cowpox virus Crma protein
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-1.
- Isotype: Rabbit Ig
- Gene: P29466
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)