Product & ReviewsAntibodies
Caspase-10 Antibody
Product Details
- Cat. No.
- 250571
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Caspase 10 is involved in the activation cascade of caspases responsible for apoptosis execution. It cleaves and activates caspase-3, -4, -6, -7, -8, and -9 and is recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. Caspase-10 participates in the granzyme B apoptotic pathways, and hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-10.
- Isotype: Rabbit Ig
- Gene: Q92851
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)