Caspase-2 Rabbit mAb
Product Details
- Cat. No.
- A4888
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rabbit
Western blot - Caspase-2 pAb (A4888)
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Description
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Biological Information
- Clonality: Monoclonal
- Host: Rabbit
- Reactivity: Human, Rat
