Caspase-4 Rabbit pAb
Product Details
- Cat. No.
- A6495
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - Caspase-4 antibody (A6495)
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Description
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
