Cathepsin D Antibody
Product Details
- Cat. No.
- 251720
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Cathepsin D is an acid protease active in intracellular protein breakdown. Cathepsin D is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Cathepsin D consists of a light chain and a heavy chain. Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10), also known as neuronal ceroid lipofuscinosis due to cathepsin D deficiency. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material. This results in seizures, dementia, visual loss, and/or cerebral atrophy.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Human liver cathepsin D.
- Clone: CP-D13
- Isotype: Mouse IgG2a
- Gene: P07339
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)