Product & ReviewsAntibodies
CD103-FITC, 2G5, 100 Tests, CE
Product Details
- Cat. No.
- B49222
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD103 antigen was originally described as the human mucosal antigen 1 (HML-1) and was subsequently proved to be the integrin αE subunit. CD103 is composed of a 150 kDa chain associated with a 25 kDa chain by a disulfide bond. It is expressed as a heterodimer in association with the integrin β7 chain. CD103 is expressed on mucosa-associated T lymphocytes and activated cells. This human intra-epithelial lymphocyte marker is expressed in very few resting peripheral blood lymphocytes. αEβ7 binds to E-cadherin on epithelial cells. Activation and TGFβ-1 induce CD103 expression.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rhesus Monkey, Sooty Mangabey
- Antigen: CD103
- Clone: 2G5
- Conjugate: FITC
- Isotype: IgG2a
Handling
- Quantity: 100 tests
Applications
- Flow Cytometry (FC)
