Product & ReviewsAntibodies

CD103-FITC, 2G5, 2 mL, ASR

Product Details

Cat. No.
IM1856U
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD103 antigen was originally described as the human mucosal antigen 1 (HML-1) and was subsequently proved to be the integrin αE subunit. CD103 is composed of a 150 kDa chain associated with a 25 kDa chain by a disulfide bond. It is expressed as a heterodimer in association with the integrin β7 chain. CD103 is expressed on mucosa-associated T lymphocytes and activated cells. This human intra-epithelial lymphocyte marker is expressed in very few resting peripheral blood lymphocytes. αEβ7 binds to E-cadherin on epithelial cells. Activation and TGFβ-1 induce CD103 expression.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Rhesus Monkey, Sooty Mangabey
  • Antigen: CD103
  • Clone: 2G5
  • Conjugate: FITC
  • Isotype: IgG2a

Handling

  • Quantity: 2 mL

Applications

  • Flow Cytometry (FC)
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