Product & ReviewsAntibodies
CD103-UNLB, 2G5, 0.2 mg, RUO
Product Details
- Cat. No.
- IM0318
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
The CD103 antigen was originally described as the human mucosal antigen 1 (HML-1) and was subsequently proved to be the integrin αE subunit. CD103 is composed of a 150 kDa chain associated with a 25 kDa chain by a disulfide bond. It is expressed as a heterodimer in association with the integrin β7 chain. CD103 is expressed on mucosa-associated T lymphocytes and activated cells. This human intra-epithelial lymphocyte marker is expressed in very few resting peripheral blood lymphocytes. αEβ7 binds to E-cadherin on epithelial cells. Activation and TGFβ-1 induce CD103 expression.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rhesus Monkey, Sooty Mangabey
- Antigen: CD103
- Clone: 2G5
- Conjugate: Purified
- Isotype: IgG2a
Handling
- Quantity: 0.2 mg
Applications
- Flow Cytometry (FC)