Product & ReviewsAntibodies

CD105 Antibody

Product Details

Cat. No.
251222
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

The CD105 antigen (endoglin) is a major glycoprotein of the vascular endothelium with a role in integrins and RGD receptors for endothelial cell adhesion. CD105 forms heteromeric complex with signaling receptors for transforming growth factor-beta. CD105 expression is restricted to endothelial cells in all tissues except bone marrow. Defects in CD105 are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1).

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Bovine, Chicken, Human, Mouse, Pig (Swine), Rabbit (Lapine), Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD105.
  • Isotype: Rabbit Ig
  • Gene: P17813

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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