Product & ReviewsAntibodies
CD105 Antibody
Product Details
- Cat. No.
- 251222
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
The CD105 antigen (endoglin) is a major glycoprotein of the vascular endothelium with a role in integrins and RGD receptors for endothelial cell adhesion. CD105 forms heteromeric complex with signaling receptors for transforming growth factor-beta. CD105 expression is restricted to endothelial cells in all tissues except bone marrow. Defects in CD105 are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Chicken, Human, Mouse, Pig (Swine), Rabbit (Lapine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD105.
- Isotype: Rabbit Ig
- Gene: P17813
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)