CD11a-FITC, 25.3, 2 mL, ASR
Product Details
- Cat. No.
- IM0860U
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD11a (αL integrin, LFA-1 α chain) is a member of the integrin family. Like some other leucocyte integrins (CD11b, CD11c, CD11d), CD11a is non-covalently associated with the β2 integrin subunit CD18. CD11a is a transmembrane glycoprotein of 170 kDa, mainly expressed by leucocytes including monocytes, macrophages, neutrophils, eosinophils, basophils, B and T lymphocytes. Activated platelets also express CD11a and CD18. LFA-1 (CD11a/CD18) promotes homotypic adhesion between lymphoid cells and heterotypic adhesion of leucocytes to the vascular endothelium. LFA-1's known ligands are Intercellular Adhesion Molecules (ICAM): ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD11a
- Clone: 25.3
- Conjugate: FITC
- Isotype: IgG1
Handling
- Quantity: 2 mL
Applications
- Flow Cytometry (FC)
