CD11b Antibody
Product Details
- Cat. No.
- 251389
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
CD11b is involved in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD11b is identical with CR-3, the receptor for the iC3b fragment of the third complement component. Genetic variations in CD11b have been associated with susceptibility to systemic lupus erythematosus type 6 (SLEB6). SLEB6 is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD11b.
- Isotype: Rabbit Ig
- Gene: P11215
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)