Product & ReviewsAntibodies
CD14 (5A3) Antibody
Product Details
- Cat. No.
- 252612
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, to promote the phagocytic uptake of bacteria or LPS coated particles by macrophages.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of human CD14 expressed in E. coli.
- Clone: 5A3
- Isotype: Mouse IgG1
- Gene: P08571, NP_000582
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)