Product & ReviewsAntibodies
CD141-FITC, M80, 1 mL, ASR
Product Details
- Cat. No.
- B43289
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD141, also known as thrombomodulin (TM) and BDCA-3, is an endothelial cell surface receptor. It is a 75 kD type I membrane glycoprotein and members of C-type lectin family. Two major isoforms exist, differentiated by the presence or not of sulfated glycosaminoglycan at Ser/Thr region. CD141 antigen is expressed on neutrophils, monocytes, platelets, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. It is a cofactor in the activation of protein C and initiation of the protein C anticoagulant pathway by binding to its ligand thrombin.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD141
- Clone: M80
- Conjugate: FITC
- Isotype: IgG1
Handling
- Quantity: 1 mL
Applications
- Flow Cytometry (FC)