Product & ReviewsAntibodies

CD146-PE, TEA 1/34, 2 mL, ASR

Product Details

Cat. No.
A07483
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

The CD146 molecule, also known as S-Endo, is a single chain transmembrane glycoprotein with a molecular weight of 118 kDa, belonging to the immunoglobulin superfamily (IgS). The extracellular structure consists of five Ig-like domains: two V-type, and three C2-type Ig-like domains. The CD146 antigen is related to cell adhesion molecules of the IgS family and its presence is concentrated at regions of cell-cell contact, confirming its role in adhesion and particularly in maintenance of monolayer integrity. CD146 is constitutively expressed in the endothelium, and is also observed on other cell types such as smooth muscle cells, and intermediate trophoblasts. Among peripheral whole blood leucocytes, CD146 expression is not detected, except on a subset of activated T-lymphocytes.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD146
  • Clone: TEA 1/34
  • Conjugate: PE
  • Isotype: IgG2a

Handling

  • Quantity: 2 mL

Applications

  • Flow Cytometry (FC)
Specificity rating
Sensitivity rating
Quality rating
Write your own review

Product Overview

Links