CD16-APC-A750, 3G8, 0.5 mL, ASR
Product Details
- Cat. No.
- A66330
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD16 antigen is the low-affinity receptor for IgG (FcγRIII). The CD16 antigen exists in two different forms encoded by two different genes: FcγRIIIA (or III-2) and FcγRIIIB (or III-1). The genetic heterogeneity of CD16 generates alternative membrane-anchored molecules. One is a transmembrane form (FcγRIIIA, 50-65 kDa) expressed on NK cells, monocytes and macrophages. The other is a glycosylphosphatidylinositol (GPI)-anchored form (FcγRIIIB, 48 kDa) only expressed on neutrophils. It has been shown that the CD16 antigen can be non-covalently associated within the membrane of NK cells, to a disulfide-linked homo or heterodimer made from the 16 kDa CD3ζ chain and the FcεRIγchain. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Baboon, Baboon, Capuchin Monkey, Cynomolgus Monkey, Dog (Canine), Horse (Equine), Human, Marmoset, Rhesus Monkey, Squirrel Monkey
- Antigen: CD16
- Clone: 3G8
- Conjugate: APC-Alexa Fluor* 750
- Isotype: IgG1
Handling
- Quantity: 0.5 mL
Applications
- Flow Cytometry (FC)
