Product & ReviewsAntibodies

CD161-APC-A750, 191B8, 0.5 mL, ASR

Product Details

Cat. No.
B30630
Type
Flow Cytometry Reagents
Clonality
Monoclonal
Host
Mouse
Beckman Coulter Life Sciences

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Description

The CD161 antigen is also designated as the NKR-P1A molecule. CD161 is a type II integral membrane protein expressed as a monomer of 44 kDa or as a disulphide-linked homodimer of 80 kDa. The carboxy-terminal extracellular domain is homologous to Ca++-dependent (C-type) lectin superfamily. CD161 is an activatory NK receptor, but in contrast with other NK receptors such as KIR (p58, p70, p140) and CD94/NKG2, CD161-mediated activation is not HLA-dependent. CD161 is expressed on all NK cells and on sub-populations of T lymphocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD161
  • Clone: 191B8
  • Conjugate: APC-Alexa Fluor* 750
  • Isotype: IgG2a

Handling

  • Quantity: 0.5 mL

Applications

  • Flow Cytometry (FC)
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