Product & ReviewsAntibodies
CD161-PE, 191B8, 1 mL, ASR
Product Details
- Cat. No.
- IM3450
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The CD161 antigen is also designated as the NKR-P1A molecule. CD161 is a type II integral membrane protein expressed as a monomer of 44 kDa or as a disulphide-linked homodimer of 80 kDa. The carboxy-terminal extracellular domain is homologous to Ca++-dependent (C-type) lectin superfamily. CD161 is an activatory NK receptor, but in contrast with other NK receptors such as KIR (p58, p70, p140) and CD94/NKG2, CD161-mediated activation is not HLA-dependent. CD161 is expressed on all NK cells and on sub-populations of T lymphocytes.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD161
- Clone: 191B8
- Conjugate: PE
- Isotype: IgG2a
Handling
- Quantity: 1 mL
Applications
- Flow Cytometry (FC)