Product & ReviewsAntibodies
CD181 Antibody
Product Details
- Cat. No.
- 251385
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
C-X-C chemokine receptor type 1 (CXC-R1, CD181) is a receptor to interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to CD181 causes activation of neutrophils. This response is mediated via a G-protein cascade that activates a phosphatidylinositol-calcium second messenger system. CD181 binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD181.
- Isotype: Rabbit Ig
- Gene: P25024
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)