Product & ReviewsAntibodies
CD183 Antibody
Product Details
- Cat. No.
- 251386
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
C-X-C chemokine receptor type 3 (CXCR-3, CD183) is a receptor for CXCL9, CXCL10 and CXCL11 that mediates the proliferation of human mesangial cells (HMC). CD183 isoform 2 is a receptor for CXCL4 that mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC). Isoform 3 mediates the activity of CXCL11. Isoforms 1 and 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD183.
- Isotype: Rabbit Ig
- Gene: P49682
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)